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COMPOSITION COMPRISING 8-(TOSYLAMINO)QUINOLINE FOR THE PREVENTION OR TREATMENT OF INFLAMMATORY DISEASES, IMMUNE DISEASES OR TUMORS
COMPOSITION COMPRISING 8-(TOSYLAMINO)QUINOLINE FOR THE PREVENTION OR TREATMENT OF INFLAMMATORY DISEASES, IMMUNE DISEASES OR TUMORS
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机译:包含8-(甲苯磺胺)喹啉的组合物,用于预防或治疗炎症性疾病,免疫性疾病或肿瘤
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摘要
A composition comprising 8-(tosylamino)quinoline is provided to inhibit production of nitric oxide, growth of cancer cells and C6 glioma cell, production of PGE2(prostaglandin 2), and activity of IKK(I kappa B alpha kinase) and Src kinase, thereby preventing or treating inflammatory diseases, immune diseases or tumors. The composition for preventing or treating inflammatory diseases, immune diseases or tumors comprises 8-(tosylamino)quinoline or pharmaceutically acceptable salts thereof including an acid addition salt selected from hydrochloric acid, hydrobromic acid, phosphonic acid, sulfuric acid, tartaric acid, acetic acid, citric acid, malic acid, methanesulphonic acid and gluconic acid.
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