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PHOSPHINE COMPOUND, PROCESS FOR PRODUCING THE PHOSPHINE COMPOUND, AND PEROXIDE SCAVENGER USING THE PHOSPHINE COMPOUND
PHOSPHINE COMPOUND, PROCESS FOR PRODUCING THE PHOSPHINE COMPOUND, AND PEROXIDE SCAVENGER USING THE PHOSPHINE COMPOUND
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机译:磷化氢化合物,磷化氢化合物的制备方法以及使用磷化氢化合物的过氧化物清除剂
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摘要
Disclosed is a novel peroxide scavenger comprising a phosphine compound represented by general formula [I]: [I] wherein Z1 and Z2 each represent a cyclic group; Ar represents an allylene group; R represents an aliphatic hydrocarbon group; Y represents phosphorus (P), nitrogen (N), or bismuth (Bi); and R1, R2, and R3 each represent a cyclic group, particularly a peroxide scavenger that can scavenge peroxides such as active oxygen species which are produced in mitochondria upon exposure to oxidant stress and are localized in the mitochondria. The phosphine compound is oxidized by the peroxides localized in the mitochondria to increase the fluorescence intensity, whereby the peroxides are scavenged.
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