首页> 外国专利> A DEVICE AND METHOD FOR TREATING OSTEOLYSIS USING A DRUG DEPOT TO DELIVER AN ANTI-INFLAMMATORY AGENT

A DEVICE AND METHOD FOR TREATING OSTEOLYSIS USING A DRUG DEPOT TO DELIVER AN ANTI-INFLAMMATORY AGENT

机译：一种利用药物仓库治疗骨质疏松症的设备和方法，以提供抗炎药

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摘要

The present invention relates to a device and method of treating an osteo-degenerative disease followed by an optional procedure using an osteoconductive material to accelerate healing of bone tissue damaged by the disease. The device for treating the bone degenerative disease comprises an in situ drug depot that time releases at least one anti-inflammatory agent. The method for treating an osteo-degenerative disease comprising: a) the combination of at least one anti-inflammatory agent with a flowable drug carrier, b) delivering the flowable drug carrier/anti-inflammatory mixture to a bone lesion, c) in situ curing of the mixture forming a rigid drug depot, d) wherein the drug depot bio-resorbs releasing the anti-inflammatory agent over time to treat a degenerative bone disease), and e) followed by an optional treatment using an osteoconductive material in combination with a growth factor.

机译：本发明涉及一种治疗骨退化性疾病的装置和方法，其后是使用骨传导性材料以加速由该疾病损害的骨组织的愈合的可选程序。用于治疗骨变性疾病的装置包括原位药物仓库，该药物仓库随时间释放至少一种抗炎剂。该治疗骨变性疾病的方法包括：a）至少一种抗炎剂与可流动的药物载体的组合，b）将可流动的药物载体/抗炎混合物递送至骨病变，c）原位固化形成刚性药物仓库的混合物，d），其中药物仓库随着时间的流逝而生物吸收再吸收抗炎剂以治疗退化性骨疾病），和e），然后使用骨传导材料与一个增长因素。

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公开/公告号WO2008127366A3

专利类型
公开/公告日2009-09-11

原文格式PDF
申请/专利权人 WARSAW ORTHOPEDIC INC.;ZANELLA JOHN M.;
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申请/专利号WO2007US81448
发明设计人 ZANELLA JOHN M.;
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申请日2007-10-16
分类号A61L27/54;A61K9/00;A61L27/58;
国家 WO
入库时间 2022-08-21 19:21:32

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