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FORMS OF MULTI-PAPER MEDICINES CONTAINING ACTIVE PRINCIPLES, THAT INCLUDE A NEUTRAL NUCLEUS AND AN INTERIOR AND EXTERIOR COATING OF METOLRILATE COPOLIMEROS AND MONOMEROS.
FORMS OF MULTI-PAPER MEDICINES CONTAINING ACTIVE PRINCIPLES, THAT INCLUDE A NEUTRAL NUCLEUS AND AN INTERIOR AND EXTERIOR COATING OF METOLRILATE COPOLIMEROS AND MONOMEROS.
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机译:包含活性成分的多种药物的形式,包括中性核以及间苯二酚的结肠炎和莫诺莫司的内外涂层。
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摘要
Multilayer drug form, formed by a) a neutral core, b) an inner coating based on a methacrylate copolymer c) an outer coating based on a copolymer, which is constituted by 40 to 95% by weight of C1-alkyl esters C4 of the radical polymerized acrylic or methacrylic acid and 5 to 60% by weight of (meth) acrylate monomers with an anionic group in the alkyl moiety characterized in that the inner lining is essentially composed of a methacrylate copolymer, which is formed at least at 90% by weight by (meth) acrylate monomers with neutral moieties, it exhibits a minimum film-forming temperature according to DIN 53787 of 30 ° C maximum and contains the pharmaceutical active ingredient in combination.
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