首页> 外国专利> METHOD OF PROGNOSING EFFICACY OF TREATMENT AND DEVELOPMENT OF SEPTIC COMPLICATIONS IN PATIENTS WITH SEVERE ACUTE PANCREATITIS

METHOD OF PROGNOSING EFFICACY OF TREATMENT AND DEVELOPMENT OF SEPTIC COMPLICATIONS IN PATIENTS WITH SEVERE ACUTE PANCREATITIS

机译:重症急性胰腺炎的治疗效果和并发症的发生的方法

摘要

The invention belongs to the field of medicine, surgery, reanimatology, and it is relevant to acute pancreatitis and severe form treatment efficacy thereof. Object matter of this invention is development of method for treatment efficacy assessment and septic complications in patients with severe acute pancreatitis. The intention is achieved by determination of inter IL-6 level in blood serum by using immunoenzymatic method ELISA. Then is performed hyperbaric oxygenation course 2 times per day with 8 h interval between each session. After that repeatedly is determined IL-6 level, and if after the third hyperbaric oxygenation session the level of IL-6 is smaller than 1300 pg/ml, the development risk of septic complications is prognosed. IL-6 level determination in blood serum after the third hyperbaric oxygenation session could be used as screening test for assessment necrosis and infection risk of liquid collection in case of acute pancreatitis. It will justify additional monitoring of said complications, preventive prescribing antibiotics for patients with such complications, as well as other measures which enhance oxygen-delivery into tissues.
机译:本发明属于医学,外科,肾脏病学领域,涉及急性胰腺炎及其严重形式的治疗功效。本发明的目的是开发用于治疗重症急性胰腺炎患者的疗效和脓毒症并发症的方法。通过使用免疫酶法ELISA测定血清中IL-6水平来实现该目的。然后每天进行2次高压氧疗程,每次疗程间隔8小时。此后反复确定IL-6水平,如果在第三次高压氧疗后IL-6水平小于1300 pg / ml,则可预示脓毒症并发症的发生风险。第三次高压氧治疗后血清中IL-6水平的测定可用作筛查试验,以评估急性胰腺炎时坏死和液体收集的感染风险。它将有理由对上述并发症进行额外的监测,为患有此类并发症的患者开具预防性的处方抗生素,以及其他可增强向组织供氧的措施。

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