首页> 外国专利> USE OF PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE FOR THE MANUFACTURE OF A MEDICAMENT FOR TREATMENT OF RESTENOSIS AND MALIGNANCIES

USE OF PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE FOR THE MANUFACTURE OF A MEDICAMENT FOR TREATMENT OF RESTENOSIS AND MALIGNANCIES

机译：磷脂酰肌醇-4,5-双磷酸酯在制备用于再狭窄和恶性肿瘤治疗的药物中的用途

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摘要

A method for the treatment of, or prevention of a disease and/or condition in a patient which is treatable or preventable by receptor mediated treatment is provided, the method comprising the administration of an effective amount of a medicine and/or therapeutic agent with an effective amount of a binding agent (other than hyaluronan, a pharmaceutically acceptable salt thereof or other such forms of hyaluronic acid) which binding agent is mixed with the medicine and/or therapeutic agent and which binding agent binds at the site of the disease or condition with at least one of the group of binding domains selected from: (a) RSHKTRSHH {Single-Letter Code of Amino Acids} also identified as: Arg-Ser-His-Lys-Thr-Arg-Ser-His-His {Three-Letter Code of Amino Acids} also identified as: uCGC-TCG-CAC-AAG-ACC-AGG-TCG-CAC-CAC/u (Another Code); (b) RPHFHKR {Single Letter Code of Amino Acids} also identified as: Arg-Pro-His-Phe-His-Lys-Arg {Three-Letter Code of Amino Acids} also identified as uCGG-CCC-CAC-TTC-CAC-AAG-CGG/u (Another Code).

机译：提供了一种用于治疗或预防可通过受体介导的治疗来治疗或预防的疾病和/或病症的方法，该方法包括将有效量的药物和/或治疗剂与一种或多种药物一起给药。有效量的粘合剂（透明质酸，其药学上可接受的盐或其他此类形式的透明质酸），该粘合剂与药物和/或治疗剂混合，并且该粘合剂在疾病或病症部位结合具有选自以下的结合域中的至少一个的结合域：（a）RSHKTRSHH {氨基酸的单字母密码}也被标识为：Arg-Ser-His-Lys-Thr-Arg-Ser-His-His {Three-氨基酸字母代码}也标识为： CGC-TCG-CAC-AAG-ACC-AGG-TCG-CAC-CAC （另一个代码）; （b）RPHFHKR {氨基酸单字母密码}也标识为：Arg-Pro-His-Phe-His-Lys-Arg {氨基酸三字母密码}也标识为 CGG-CCC-CAC- TTC-CAC-AAG-CGG （另一个代码）。

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公开/公告号HU226598B1

专利类型
公开/公告日2009-04-28

原文格式PDF
申请/专利权人 JAGOTEC AG.;
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申请/专利号HU19990002059
发明设计人 TURLEY EVA;
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申请日1996-12-23
分类号A61K31/6615;A61K38;A61K31;A61K31/66;A61K31/661;A61K31/715;A61K31/726;A61K31/728;A61K47/54;A61P9;A61P9/10;A61P35;C07C31/24;C07C31/27;C07F9/117;C07K7/06;C07K14/47;C07K14/705;
国家 HU
入库时间 2022-08-21 19:27:53

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