首页> 外国专利> Composition of microparticles of water-insoluble substance, pharmaceutical composition, process for preparing stable particles, microparticles of water-insoluble or poorly soluble substance per se, composition containing such microparticles and proce

Composition of microparticles of water-insoluble substance, pharmaceutical composition, process for preparing stable particles, microparticles of water-insoluble or poorly soluble substance per se, composition containing such microparticles and proce

机译：水不溶性物质的微粒的组成，药物组合物，稳定颗粒的制备方法，水不溶性或难溶性物质的微粒本身，含有该微粒的组合物和方法

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摘要

In the present invention, there is disclosed a composition of microparticles of a water-insoluble substance comprising particles of an industrially useful water-insoluble or poorly soluble compound, a phospholipid and at least one non-ionic, anionic or cationic surfactant, in which the surfactant or surfactants provide volume-weighted mean particle size values of the water-insoluble compound at least 50% smaller than particles produced without the presence of the surfactant using the same energy input.

机译：在本发明中，公开了一种水不溶性物质的微粒组合物，其包含工业上有用的水不溶性或难溶性化合物，磷脂和至少一种非离子，阴离子或阳离子表面活性剂的颗粒，其中一种或多种表面活性剂提供的水不溶性化合物的体积加权平均粒径值比使用相同能量输入时不存在表面活性剂的情况下产生的颗粒小至少50％。

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公开/公告号CZ299790B6

专利类型
公开/公告日2008-11-26

原文格式PDF
申请/专利权人 SKYEPHARMA CANADA INC.;
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申请/专利号CZ19990000596
发明设计人 PARIKH INDU;SELVARAJ ULAGARAJ;
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申请日1997-03-28
分类号A61K9/50;A61K9/51;A61K9/10;A61K9/14;A61K47/06;A61K49;A61K49/04;
国家 CZ
入库时间 2022-08-21 19:28:17

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