首页>
外国专利>
Method for producing a replicative influenza virus particle without the use of helper virus, replicative influenza virus particle, Cell, composition, use of a composition, Method for generating immunological protection against infection of an individual with an influenza virus, , Nucleic acid
Method for producing a replicative influenza virus particle without the use of helper virus, replicative influenza virus particle, Cell, composition, use of a composition, Method for generating immunological protection against infection of an individual with an influenza virus, , Nucleic acid
METHOD TO PRODUCE A REPLICATIVE INFLUENZA VIRUS PARTICLE WITHOUT THE USE OF AUXILIARY VIRUS, REPLICATIVE INFLUENCE VIRUS PARTICLE, CELL, COMPOSITION, USE OF A INFUSED GARDEN IMPRODUCTION METHOD , NUCLEIC ACID. The invention relates to the field of influenza vaccine production. Influenza vaccines have been produced in embryonated chicken eggs for over 50 years, but considerable efforts have recently been made to develop cell culture systems for vaccine production. The invention provides a nucleic acid comprising an influenza gene segment and a bacteriophage polymerase promoter or complementary strand of said nucleic acid, and a cell comprising such a nucleic acid capable of producing the desired influenza virus. Furthermore, the invention provides a composition comprising a cell or material derived from a cell according to the invention, and a virus or material derived from a viral particle according to the invention.
展开▼
