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A component of anti pertussis Vaccine and simplified procedure for obtaining Pertactin (PRN) of Bordetella pertussis

机译:抗百日咳疫苗的成分和获得百日咳博德特氏菌百日咳杆菌粘附素(PRN)的简化程序

摘要

A component of anti pertussis Vaccine obtaining Antigen Pertactin (PRN) from Bordetella pertussis. A simplified process for Extraction and purification of Pertactin (PRN). Pertactin obtained by this procedure has a higher level of Purity Of 90% and the procedure used in this prevents loss of PRN to avoid Complex Processing steps.The Outer Membrane Protein (OMP) Purified by this procedure uses a simplified process and is useful in the preparation of anti pertussis acellular Vaccines, both alone and in combinations of Vaccines.Claim 1: a procedure to use the component of vaccine according to claim 1, characterized in that it comprises administering to a subject in need thereof a quantity of the component of the vaccine.
机译:从百日咳博德特氏菌获得抗原百日咳杆菌粘附素(PRN)的百日咳疫苗的成分。百日咳杆菌粘附素(PRN)的提取和纯化的简化过程。通过此步骤获得的百日咳杆菌粘附素的纯度更高,达到90%,并且该步骤可防止PRN丢失,从而避免了复杂的加工步骤。通过此步骤纯化的外膜蛋白(OMP)使用了简化的过程,可用于权利要求1:使用权利要求1的疫苗组分的方法,其特征在于,它包括向有需要的受试者施用一定量的百日咳疫苗组分。疫苗。

著录项

  • 公开/公告号AR067471A1

    专利类型

  • 公开/公告日2009-10-14

    原文格式PDF

  • 申请/专利权人 PANACEA BIOTEC LTD.;

    申请/专利号AR2008P102932

  • 发明设计人 MAGO M. L.;JAIN RAJESH;

    申请日2008-07-07

  • 分类号A61K39/10;A61K35/74;A61P31/04;

  • 国家 AR

  • 入库时间 2022-08-21 19:28:40

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