首页> 外国专利> Method of improving cumulative embryo score and quantity of fertilized oocytes, increasing euploidy rate and of normalizing ovarian function using an androgen such as dehydroepiandrosterone

Method of improving cumulative embryo score and quantity of fertilized oocytes, increasing euploidy rate and of normalizing ovarian function using an androgen such as dehydroepiandrosterone

机译:使用雄激素(例如脱氢表雄酮)提高累积胚胎评分和受精卵母细胞数量,提高整倍性率以及使卵巢功能正常化的方法

摘要

A method of improving cumulative embryo score may comprise administering an androgen to a human female, for example, DHEA, for at least about four consecutive months followed by harvesting and fertilizing oocytes and forming embryos. Between about 50 mg and about 100 mg of DHEA may be administered to a human female per day. Moreover, a method of increasing the quantity of fertilized oocytes in one cycle of in vitro fertilization may comprise administering an androgen to a human female for at least about four consecutive months, harvesting and fertilizing the oocytes. Furthermore, a method of increasing the quantity of day 3 embryos from one cycle of in vitro fertilization may comprise administering an androgen for at least about four consecutive months, harvesting and fertilizing the oocytes and forming day 3 embryos. A method of normalizing ovarian DHEA also may include administering an androgen for at least about four consecutive months. A method of increasing the euploidy rate in embryos may include administering an androgen for at least about four consecutive weeks.
机译:一种改善累积胚胎评分的方法可以包括对人类女性例如DHEA施用雄激素至少约连续四个月,然后收获卵子并使其受精并形成胚胎。每天可以向人类女性施用约50mg至约100mg的DHEA。此外,一种在一个体外受精周期中增加受精卵母细胞数量的方法可包括向雄性女性施用雄激素至少约连续四个月,收获并使卵母细胞受精。此外,一种从一个周期的体外受精中增加第3天胚胎数量的方法可包括连续至少约四个月施用雄激素,收获和使卵母细胞受精并形成第3天胚胎。卵巢DHEA标准化的方法还可以包括连续至少约四个月施用雄激素。增加胚胎中整倍性率的方法可包括连续至少约四周施用雄激素。

著录项

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号