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Transcriptional Regulation of Cytokines by LITAF and STAT (6)(B)

机译：LITAF和STAT对细胞因子的转录调控（6）（B）

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摘要

The present invention relates to novel proteins (LITAF and STAT6(B)) and the nucleotide sequences encoding the same. The present invention also relates to the use of the novel peptides and nucleotide sequences of the present invention, or functional fragments thereof, for the regulation of cytokine expression. The present invention also relates to the use of the novel proteins and nucleotides sequences of the present invention for the regulation of inflammatory responses in mammals including the regulation of angiogenesis and tubulogenesis. Also in this regard, the present invention relates to the generation of null mutant animals deficient in the expression of one or both of the proteins of the present invention.

机译：本发明涉及新型蛋白质（LITAF和STAT6（B））及其编码核苷酸序列。本发明还涉及本发明的新型肽和核苷酸序列或其功能片段在调节细胞因子表达中的用途。本发明还涉及本发明的新型蛋白质和核苷酸序列在调节哺乳动物中的炎症反应，包括调节血管生成和微管生成中的用途。同样在这方面，本发明涉及缺失本发明的一种或两种蛋白的表达的无效突变动物的产生。

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公开/公告号US2009062190A1

专利类型
公开/公告日2009-03-05

原文格式PDF
申请/专利权人 SALOMON AMAR;XIAOREN TANG;
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申请/专利号US20060884854
发明设计人 SALOMON AMAR;XIAOREN TANG;
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申请日2006-02-23
分类号A61K38;C12N15;C07K14;C12N5/06;A61P31;A61K31/7088;A01K67/027;C40B30/04;
国家 US
入库时间 2022-08-21 19:31:06

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