首页> 外国专利> MULTIPLE MYELOMA AND AL AMYLOID IMMUNOTHERAPY TARGETING IMMUNOGLOBULIN LIGHT CHAINS AND USES THEREOF

MULTIPLE MYELOMA AND AL AMYLOID IMMUNOTHERAPY TARGETING IMMUNOGLOBULIN LIGHT CHAINS AND USES THEREOF

机译:靶向骨髓免疫球蛋白轻链的多发性骨髓瘤和淀粉样蛋白免疫疗法及其用途

摘要

The present invention relates generally to the prevention and treatment of disease states, and more particularly to the treatment and prevention of plasma cell disorders and plasma cell dyscrasias and other malignancies, amyloidosis and amyloid-associated diseases. In particular, the present invention relates to methods and compositions comprising immunogenic peptides for the treatment and prevention of diseases and malignancies, for example plasma cell disorders, plasma cell dyscrasias and amyloidosis or amyloid-associated diseases. The present invention also provides methods for an assay to screen for therapeutic vaccines for plasma cell disorders, plasma cell dyscrasias and amyloidosis or amyloid-associated diseases.
机译:本发明总体上涉及疾病状态的预防和治疗,并且更具体地涉及浆细胞疾病和浆细胞发育不良和其他恶性肿瘤,淀粉样变性病和淀粉样蛋白相关疾病的治疗和预防。特别地,本发明涉及用于治疗和预防疾病和恶性肿瘤的免疫原性肽的方法和组合物,所述疾病和恶性肿瘤例如浆细胞疾病,浆细胞发育不良和淀粉样变性或与淀粉样蛋白相关的疾病。本发明还提供了用于筛选针对浆细胞疾病,浆细胞发育不良和淀粉样变性或淀粉样蛋白相关疾病的治疗性疫苗的测定方法。

著录项

  • 公开/公告号US2009028847A1

    专利类型

  • 公开/公告日2009-01-29

    原文格式PDF

  • 申请/专利权人 DAVID H. SHERR;AMANDA FLIES;

    申请/专利号US20080102691

  • 发明设计人 DAVID H. SHERR;AMANDA FLIES;

    申请日2008-04-14

  • 分类号A61K39/395;A61P35;A61K39/44;C12Q1/02;

  • 国家 US

  • 入库时间 2022-08-21 19:31:52

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