首页> 外国专利> Immunoassay for the Simultaneous Immunochemical Determination of an Analyte (Antigen) and a Treatment Antibody Targeting the Analyte in Samples (Recovery Immunoassay)

Immunoassay for the Simultaneous Immunochemical Determination of an Analyte (Antigen) and a Treatment Antibody Targeting the Analyte in Samples (Recovery Immunoassay)

机译:同时分析样品(抗原)和靶向样品中分析物的治疗抗体的免疫分析(回收免疫分析)

摘要

The invention relates to an immunoassay for the simultaneous immunochemical determination of an analyte (antigen) and a treatment antibody targeting the analyte in samples (recovery immunoassay). The inventive immunoassay comprises an optionally marked catcher antibody bound to a surface, a marked treatment antibody, or a marked antibody which has the same binding epitope as the treatment body, an antigen that binds to the catcher antibody and the treatment antibody in the region of various epitopes, and in this way forms an immunochemical sandwich, a solution of the unmarked treatment antibody of a known concentration, and an antigen solution to be added to the samples. The invention can be applied to the fields of medical diagnosis, treatment control and pharmacological research.
机译:本发明涉及用于同时免疫化学测定分析物(抗原)和靶向样品中分析物的治疗抗体的免疫测定法(回收免疫测定法)。本发明的免疫测定法包括与表面结合的任选标记的捕获抗体,标记的治疗抗体或具有与治疗体相同的结合表位的标记的抗体,与捕获抗体结合的抗原和在区域中的治疗抗体。各种表位,并以此方式形成免疫化学夹心,已知浓度的未标记处理抗体溶液和待添加至样品的抗原溶液。本发明可以应用于医学诊断,治疗控制和药理研究领域。

著录项

  • 公开/公告号US2008280311A1

    专利类型

  • 公开/公告日2008-11-13

    原文格式PDF

  • 申请/专利权人 PAVEL STROHNER;

    申请/专利号US20060095776

  • 发明设计人 PAVEL STROHNER;

    申请日2006-11-29

  • 分类号G01N33/00;

  • 国家 US

  • 入库时间 2022-08-21 19:34:16

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