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CARBOXYLATED GLUCOSAMINE COMPOUNDS FOR INHIBITING THE ACTIVATION AND EXPRESSION OF MATRIX METALLOPROTEINASE-9 IN HUMAN FIBROSARCOMA CELLS AND MATRIX METALLOPROTEINASE-9 INHIBITORS CONTAINING THE SAME
CARBOXYLATED GLUCOSAMINE COMPOUNDS FOR INHIBITING THE ACTIVATION AND EXPRESSION OF MATRIX METALLOPROTEINASE-9 IN HUMAN FIBROSARCOMA CELLS AND MATRIX METALLOPROTEINASE-9 INHIBITORS CONTAINING THE SAME
The present invention relates to the CGlc compound for inhibiting the expression and activation of MMP-9 in HT1080 and the MMP-9 inhibitor comprising the CGlc compound as an effective ingredient, which can inhibits the expression of AP-1 in Ht1080 to effectively inhibit the expression and activation of MMP-9 such that it is effectuated in treating a wound, metastasis, rheumatoid arthritis, inflammation, hyperparathyroidism, diabetes, cornel ulcer, osteoporosis, stomach ulcer, trauma, pimple, burn, periodontal disease, arteriosclerosis or fracture.
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