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Quantum dot-DNA-metallic nanoparticle ensemble as fluorescent nanosensor system for multiplexed detection of heavy metals
Quantum dot-DNA-metallic nanoparticle ensemble as fluorescent nanosensor system for multiplexed detection of heavy metals
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机译：量子点-DNA-金属纳米粒子集合作为荧光纳米传感器系统用于重金属的多重检测
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摘要
A first embodiment is a quantum dot-DNA-metallic ensemble that can be used as a fluorescent nanosensor for multiplexed detection of the presence and the quantity of one or more target ions in a single assay. In this design, DNA-functionalized multi-colored quantum dots are used as energy donors and god nanoparticles are used as energy acceptors. This design allows for flexibility and a selective binding of a target ion to oligonucleotides, drives the formation of DNA helixes, which bring a quantum dot and metallic nanoparticle into close proximity, leading to a fluorescence emission energy transfer. The energy transfer is detected and the presence and the quantity of the target ion can be confirmed.
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