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NEW PREPARATIVE SUBSTANCE FORM CHARACTERISED BY NOOTROPIC AND NEUROMODULATING ACTIVITY, AND RELATED METHOD OF PRODUCTION

机译:通过营养调节和神经调节活性表征的新型制备物质形式及其生产方法

摘要

FIELD: medicine; pharmacology.;SUBSTANCE: purpose of given invention lies in development of stable preparative form of injection phenotropyl with high biologicale accessibility, and related method of production. Set purpose is achieved by solution-like injection agent containing phenotropyl and solvent consisting of mixed polyethylene glycol (PEG), ethyl alcohol and injection water. Solution is made phenotropyl dissolved in ethyl alcohol, added with polyethylene glycol and injection water followed with microfiltering sterilisation, preferably through filter with pore sizes 0.1 -1.0 mcm, most preferably through filter with pore sizes 0.45 mcm.;EFFECT: reduced disabling probability and hospitalisation time.;5 ex, 2 tbl, 4 cl
机译:领域:医学;药物:物质:本发明的目的在于开发具有高生物可及性的稳定的注射剂苯酞的制备形式以及相关的生产方法。凝固的目的是通过包含苯甲基和包含混合的聚乙二醇(PEG),乙醇和注射用水的溶剂的溶液状注射剂来实现的。使溶液中的苯酚溶解在乙醇中,向其中加入聚乙二醇和注射用水,然后微滤灭菌,最好通过孔径为0.1 -1.0 mcm的过滤器,最优选孔径为0.45 mcm的过滤器;效果:降低致残率和住院率时间。; 5 ex,2 tbl,4 cl

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