首页> 外国专利> Method of Diagnosis of Toxicity for Polybrominated Diphenyl Ethers using Target organ-array and PBDEs-specific proteins

Method of Diagnosis of Toxicity for Polybrominated Diphenyl Ethers using Target organ-array and PBDEs-specific proteins

机译:使用靶器官阵列和PBDEs特异性蛋白诊断多溴联苯醚毒性的方法

摘要

The present invention is a protein specific to the target organ array and bromine compounds for the exposure and addiction diagnosis of bromine compounds relates to a diagnostic method using, more specifically, by confirming the change in the amount of protein showing the change by selecting a specific and organ-specific proteins sensitively affected by the bromine compound in the target organ diagnostic bromine compound exposure and addiction relates to a method of. ; This invention is a swing frame in the X receptor or apolipoprotein A-1 of the pituitary tissue, thyroid tissue of Bcl-2, or androgen UGT1A of CYP1A1 in liver tissue or prostate tissue by detecting the expression level of the receptor protein, contamination of the environment are well and makes it possible to diagnose the exposure and toxemia of mental retardation, thyroid function disorder, such as a bromine compound to cause endocrine disorders.
机译:本发明是针对靶器官阵列和溴化合物的暴露和成瘾诊断的溴化合物特异的蛋白质,其涉及一种诊断方法,更具体地讲,是通过选择特定的蛋白质来确认显示出该变化的蛋白质量的变化。与器官特异性蛋白质敏感地受溴化合物影响的靶器官中诊断溴化合物的暴露和成瘾有关的方法。 ;本发明是通过检测肝组织或前列腺组织中的垂体组织的X受体或载脂蛋白A-1,Bcl-2的甲状腺组织或CYP1A1的雄激素UGT1A的摆动框架而进行的。环境良好,可以诊断出智力低下,甲状腺功能障碍(如引起内分泌失调的溴化合物)的暴露和毒血症。

著录项

  • 公开/公告号KR100858168B1

    专利类型

  • 公开/公告日2008-09-17

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20060138940

  • 申请日2006-12-29

  • 分类号G01N33/68;G01N33/53;

  • 国家 KR

  • 入库时间 2022-08-21 19:51:39

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