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METHODS AND COMPOSITIONS FOR THE PREDICTION OF RESPONSE TO TRASTUZUMAB CONTAINING CHEMOTHERAPY REGIMEN IN MALIGNANT NEOPLASIA
METHODS AND COMPOSITIONS FOR THE PREDICTION OF RESPONSE TO TRASTUZUMAB CONTAINING CHEMOTHERAPY REGIMEN IN MALIGNANT NEOPLASIA
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机译:预测恶性肿瘤患者对包含曲妥珠单抗的化疗方案反应的方法和成分
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摘要
The invention relates to methods and compositions for the prediction, diagnosis, prognosis, prevention and treatment of neoplastic disease. Neoplastic disease is often caused by chromosomal rearrangements which lead to over- or underexpression of the rearranged genes. The invention discloses genes which are overexpressed in neoplastic tissue and are useful as diagnostic markers and targets for treatment. Methods are disclosed for predicting, diagnosing and prognosing as well as preventing and treating neoplastic disease.
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