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Improvements to the subject of the main patent no. 200500485, 'procedure for obtaining a pharmaceutically active compound and its intermediate synthesis'.
Improvements to the subject of the main patent no. 200500485, 'procedure for obtaining a pharmaceutically active compound and its intermediate synthesis'.
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机译：对主要专利No. 200500485，“获得药物活性化合物的方法及其中间合成”。
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摘要
Improvements in the object of the principal patent No. P 200500485 for "Process for preparing a pharmaceutically active compound and its synthesis intermediate."; an improved process for obtaining the synthesis intermediate of formula (II), useful for obtaining irbesartan and, therefore, also useful in the manufacture of a medicament for the treatment of hypertension or heart failure procedure is provided.; These improvements are characterized by the fact that the reaction of 1-pentanoylamino-cyclopentenecarboxamide of formula (X) with 4-iodobenzyl bromide in the presence of a transfer catalyst phase in a biphasic reaction system takes place to obtain the intermediate (II).
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