首页> 外国专利> COSMETIC OR DERMOFARMACEUTICAL USE OF PEPTIDES FOR THE CICATRIZATION, HYDRATION AND IMPROVEMENT OF THE SKIN ASPECT DURING NATURAL OR ACCELERATED AGING (HELIODERMIA, CONTAMINATION).

COSMETIC OR DERMOFARMACEUTICAL USE OF PEPTIDES FOR THE CICATRIZATION, HYDRATION AND IMPROVEMENT OF THE SKIN ASPECT DURING NATURAL OR ACCELERATED AGING (HELIODERMIA, CONTAMINATION).

机译：在自然衰老或加速衰老（皮损，污染）过程中，肽的化妆品美容或皮肤药物的使用，用于皮肤的钙化，水合和改善。

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Peptides of the general formula R1-X-Thr-Thr-Lys- (AA) nY and their salts, where: * X represents a basic amino acid of the form D or L (lysine, arginine, histidine, ornithine, citrulline, sarcosine, statin ), * (AA) n represents a chain of n natural amino acids or not, with n varying from 0 to 5, * R1 is H or a fatty acid chain of 2 to 22 carbons, hydroxylated or not, saturated or not, linear or branched, sulphurated or not, cyclic or not, or a biotinyl group, or a urethane type protecting group used in peptide synthesis such as a benzyloxycarbonyl (Z), tert-butyloxycarbonyl (tBoc), fluorenylmethyloxycarbonyl (Fmoc), allyloxycarbonyl ( alloc), * Y = OR2 or NR2R3, R2 and / or R3 being a hydrogen atom H or an aliphatic or aromatic chain of 1 to 22 carbons, hydroxylated or not, saturated or not, linear or branched, sulphured or not, cyclic or not, except those peptides with R1 = H and X = Lys and Y = OH and with n = 0 or (AA) n = Ser when n = 1,

机译：通式R1-X-Thr-Thr-Lys-（AA）nY的肽及其盐，其中：* X表示D或L形式的碱性氨基酸（赖氨酸，精氨酸，组氨酸，鸟氨酸，瓜氨酸，肌氨酸）（他汀类药物），*（AA）n代表是否由n个天然氨基酸组成的链，n的范围为0至5，* R1为H或2至22个碳原子的脂肪酸链，羟基或不羟基，饱和或不饱和肽合成中使用的，直链或支链，未硫化或未硫化，是否环状的生物素基或氨基甲酸酯类保护基，例如苄氧羰基（Z），叔丁氧羰基（tBoc），芴基甲氧羰基（Fmoc），烯丙氧羰基（分配），* Y = OR2或NR2R3，R2和/或R3是氢原子H或1至22个碳的脂肪族或芳香族链，羟基化或非羟基，饱和与否，直链或支链，硫化或非硫化，环状或否，只有当R = 1且X = Lys且Y = OH且n = 0或（AA）n = Ser且n = 1时，

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公开/公告号ES2285859T3

专利类型
公开/公告日2007-11-16

原文格式PDF
申请/专利权人 SEDERMA;
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申请/专利号ES19990942962T
发明设计人 LINTNER KARL;
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申请日1999-09-13
分类号A61K8/04;A61K8/30;A61K8;A61K8/14;A61K8/64;A61K8/92;A61K31/74;A61K38;A61K38/08;A61P17/16;A61P43;A61Q1;A61Q1/04;A61Q1/06;A61Q1/12;A61Q5/02;A61Q19;A61Q19/02;A61Q19/08;C07K7/06;
国家 ES
入库时间 2022-08-21 20:04:30

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