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S-METHYL-DIHYDRO-ZIPRASIDONE FOR THE TREATMENT OF SCHIZOPHRENIA

机译：S-甲基-二氢齐拉西酮治疗精神分裂症

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摘要

This invention relates to pharmaceutical compositions containing S-methyl-dihydroziprasidone and to the use of such compound and its pharmaceutically acceptable salts for the treatment of psychiatric disorders. More specifically, it relates to the use of such compound and its pharmaceutically acceptable salts for the treatment of a disorder or condition selected from: schizophrenia, anxiety disorders such as generalized anxiety disorder, panic disorder, posttraumatic stress disorder and phobias (e.g., social phobia, agoraphobia etc.); psychotic episodes of anxiety: anxiety, agitation, excessive aggression, tension, or social or emotional withdrawal associated with psychosis; psychotic mood disorders such as severe major depressive disorder; mood disorders associated with psychotic disorders such as acute mania and depression associated with bipolar disorder, and mood disorders associated with schizophrenia; behavioral disturbances associated with mental retardation, autistic disorder, and conduct disorder; dementias such as dementias associated with Alzheimer's disease; drug-induced and neurodegeneration based dyskinesias; obsessive compulsive disorder; and Tourette's syndrome.

机译：本发明涉及含有S-甲基-二氢齐拉西酮的药物组合物，以及这种化合物及其药学上可接受的盐在治疗精神疾病中的用途。更具体地，本发明涉及此类化合物及其药学上可接受的盐在治疗选自以下的疾病或病症中的用途：精神分裂症，焦虑症例如广泛性焦虑症，恐慌症，创伤后应激障碍和恐惧症（例如社交恐惧症），广场恐惧症等）;焦虑的精神病发作：与精神病相关的焦虑，激动，过度攻击，紧张或社交或情感退缩;精神病性情绪障碍，例如严重的重度抑郁症;与精神病相关的情绪障碍，例如与躁郁症相关的急性躁狂和抑郁，以及与精神分裂症相关的情绪障碍;与智力低下，自闭症和品行障碍有关的行为障碍;痴呆症，例如与阿尔茨海默氏病有关的痴呆症;药物性和神经退行性运动障碍;强迫症;和图雷特氏综合症。

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公开/公告号PT1698338E

专利类型
公开/公告日2008-06-03

原文格式PDF
申请/专利权人 PFIZER PRODUCTS INC.;
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申请/专利号PT20060116051T
发明设计人 CHANDRA A. PRAKASH;TERESA A. SMOLAREK;
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申请日2001-05-28
分类号A61K31/496;A61K;A61K31/22;A61P;A61P25;A61P25/06;A61P25/14;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P27;A61P27/02;A61P27/06;C07D;C07D209/34;
国家 PT
入库时间 2022-08-21 20:06:21

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