首页> 外国专利> Pyrimidine compounds derived from - 4.6 - diamine,Inhibitors of the interactions of ATP protein kinase; Preparation procedure; and use for the treatment of diseases such as rheumatoid arthritis, diabetes mellitus,Diseases or trastorn

Pyrimidine compounds derived from - 4.6 - diamine,Inhibitors of the interactions of ATP protein kinase; Preparation procedure; and use for the treatment of diseases such as rheumatoid arthritis, diabetes mellitus,Diseases or trastorn

机译：嘧啶化合物衍生自-4.6-二胺，ATP蛋白激酶相互作用的抑制剂;准备程序;并用于治疗风湿性关节炎，糖尿病，疾病或曲妥恩等疾病

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摘要

The present invention is directed to novel bicyclic pyrimidine compounds of Formula (I) or a form or composition thereof as inhibitors of ATP-protein kinase interactions, wherein substituents on each side of the iminomethyl double bond in Formula (I) may be in the E or Z configuration; and wherein R1, R2, R3 and R4 are as defined herein.

机译：本发明涉及作为ATP-蛋白激酶相互作用抑制剂的式（I）的新型双环嘧啶化合物或其形式或组合物，其中式（I）中亚氨基甲基双键的每一侧上的取代基可以在E中或Z配置;其中R1，R2，R3和R4如本文所定义。

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公开/公告号CL2007003164A1

专利类型
公开/公告日2008-07-11

原文格式PDF
申请/专利权人 JANSSEN PHARMACEUTICA N.V.;
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申请/专利号CL20070003164
发明设计人 XU GUOZHANG.;
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申请日2007-10-31
分类号A61K31/506;A61P17/00;A61P19/02;A61P3/10;A61P35/00;C07D403/12;
国家 CL
入库时间 2022-08-21 20:08:33

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