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首页> 外国专利> Construction dendrimetrica Peptide Preparation Procedure of the Construction; Peptide; Veterinary composition comprising such Construction; use of this Peptide for Construction PPrevent foot-and-mouth disease in an animal.

Construction dendrimetrica Peptide Preparation Procedure of the Construction; Peptide; Veterinary composition comprising such Construction; use of this Peptide for Construction PPrevent foot-and-mouth disease in an animal.

机译：构建树突状多肽的制备方法;肽;包含这种结构的兽医组合物;肽在动物中预防口蹄疫的构建中的用途。

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This construct is one of formula (I) wherein: T is a peptide comprising the sequence SEQ ID NO: 1 or a fragment thereof; B is a peptide comprising the sequence SEQ ID NO: 2 or a fragment thereof; X is an acyl group bound to the N-terminal end of B; n is 3 or 4; and L corresponds to a lysine core of formula (II) where W is a linker; Z 1 -Z 4 are equal or different to each other and are selected from the group consisting of cysteine and-OH, provided that at least three of the groups Z 1 to Z 4 are cysteine; the peptide B being linked to the lysine core by its C-terminal end and the peptide T being linked to said lysine core by its N-terminal end. €ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ(X-B)n-L-T€ƒ€ƒ€ƒ€ƒ€ƒ(I)
机译：该构建体是式（I）之一，其中：T是包含序列SEQ ID NO：1的肽或其片段; B是包含序列SEQ ID NO：2或其片段的肽; X是与B的N末端结合的酰基。 n为3或4; L对应于式（II）的赖氨酸核心，其中W是连接基; Z 1 -Z 4彼此相同或不同，并且选自半胱氨酸和-OH，条件是基团Z 1至Z 4中的至少三个为半胱氨酸。肽B通过其C末端与赖氨酸核心连接，而肽T通过其N末端与所述赖氨酸核心连接。€（X-B）n-L-T€€（I）

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