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Supramolecular complexes of high stoichiometry in systems nanoagregados constituu00ecdos by chlorhexidine or tetracycline incluu00ecdos in cyclodextrin
Supramolecular complexes of high stoichiometry in systems nanoagregados constituu00ecdos by chlorhexidine or tetracycline incluu00ecdos in cyclodextrin
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机译:环糊精中洗必泰或四环素的高化学计量比超分子配合物
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摘要
Supramolecular complexes of high stoichiometry in systems nanoagregados constituu00ecdos by chlorhexidine or tetracycline incluu00ecdos in cyclodextrin inclusion complexes formed by preparation of antimicrobial and cyclodextrins (CD) mucoadesivos polymers, such as, for example, clorexid INA and cyclodextrin CiX / 225 - CD and tetracycline (TC) and cyclodextrin TC / 225 - CD, in the ratio 1: 1.Have been reported in the patent application. The complex CiX / 225 - CD (1: 1) presented activity than chlorhexidine (C x) pure when tested against bacteria Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis, Enterococcus faecalis.It was also reported higher antimicrobial activity of tetracycline complexed (TC / 225 - CD 1: 1) compared with tetracycline pure cultures of Actinobacillus actinomycetemcomitans.
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