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Cytoplasmic expression of antibodies, antibody fragments and antibody fragment fusion proteins in E. coli
Cytoplasmic expression of antibodies, antibody fragments and antibody fragment fusion proteins in E. coli
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机译:抗体,抗体片段和抗体片段融合蛋白在细胞中的细胞质表达。大肠杆菌 I>
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摘要
The invention relates to the cytoplasmic expression of antibodies, antibody fragments and antibody fragment fusion molecules in E. coli. In particular, antibody fragment fusion molecules having an antibody moiety which is directed against tumors and an enzyme moiety which cleaves a nontoxic prodrug to give the toxic drug can be advantageously prepared in this way while retaining their respective functional properties.
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