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GEDAP method (genotyping based on diagnostic amplification products) for detecting and/or preventing genotyping errors from amplification products of a polymorphic focus
GEDAP method (genotyping based on diagnostic amplification products) for detecting and/or preventing genotyping errors from amplification products of a polymorphic focus
Method GEDAP (Genotyping Based on Diagnostic Amplification Products) for detecting and/or preventing genotyping errors on the basis of the amplification products of a polymorphic locus. The method is based on the joint analysis of homoduplexes and Diagnostic Additional Products (DAPs) generated from the amplification of a polymorphic locus. The method is highly effective for detecting and/or preventing genotyping errors due to total or partial non-amplifications occurring during amplification procedures such as the Polymerase Chain Reaction (PCR).
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