首页> 外国专利> Estrogen Enhancing Differentiation of Human Mesenchymal Stromal Cells and Adipose-derived Stromal Cells

Estrogen Enhancing Differentiation of Human Mesenchymal Stromal Cells and Adipose-derived Stromal Cells

机译：雌激素增强人间质基质细胞和脂肪基质细胞的分化

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摘要

Adipose-derived stromal cells and bone marrow mesenchymal stem cells possess multiple differentiation potentials and can provide tissues for regenerative medicine and tissue engineering. The present invention provides a method of enhancing the differentiation and proliferation of adult stem cells, such as adipose-derived stromal cells and bone marrow mesenchymal stem cells, by contacting the adult stem cells with an effective amount of one or more estrogen receptor ligands. In particular, the present invention provides methods of enhancing osteogenesis and adipogenesis by contacting adipose-derived stromal cells and bone marrow mesenchymal stem cells with 17-β estradiol.

机译：脂肪基质细胞和骨髓间充质干细胞具有多种分化潜能，可以为再生医学和组织工程提供组织。本发明提供了通过使成年干细胞与有效量的一种或多种雌激素受体配体接触来增强成年干细胞如脂肪来源的基质细胞和骨髓间充质干细胞的分化和增殖的方法。特别地，本发明提供了通过使脂肪来源的基质细胞和骨髓间充质干细胞与17-β雌二醇接触来增强成骨和脂肪形成的方法。

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公开/公告号US2008118980A1

专利类型
公开/公告日2008-05-22

原文格式PDF
申请/专利权人 LIU HONG;
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申请/专利号US20070855938
发明设计人 LIU HONG;
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申请日2007-09-14
分类号C12N5/06;
国家 US
入库时间 2022-08-21 20:15:15

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