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Carohydrate-Ligand Conjugates and Their Application for the Analysis of Carbohydrate-Protein Interaction
Carohydrate-Ligand Conjugates and Their Application for the Analysis of Carbohydrate-Protein Interaction
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机译:糖-配体结合物及其在糖-蛋白质相互作用分析中的应用
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摘要
A novel ligand conjugate which is effectively utilizable for analyzing a function of a protein; a ligand-supporting object; and a method of analyzing a protein. The ligand conjugate has a structure which comprises: a linker compound having a structure represented by the following General Formula (1): (wherein n and p each is an integer of 0 to 6) in which X is a structure comprising one, two, or three hydrocarbon derivative chains which have an aromatic amino group at the end and may have a carbon-nitrogen bond in the main chain, Y is a hydro-carbon structure containing one or more sulfur atoms, and Z is a straight-chain structure comprising a carbon-carbon bond or carbon-oxygen bond; and a sugar which has a reducing end and is bonded to the linker compound through the aromatic amino group.
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机译:一种有效地用于分析蛋白质功能的新型配体缀合物;配体支持物;和分析蛋白质的方法。所述配体缀合物的结构包括:具有以下通式(1)表示的结构的连接体化合物: <图像文件=“ US20070287195A1-20071213-C00001.GIF” he =“ 13.04mm” id =“ EMI-C00001” imgContent =“ chem” imgFormat =“ GIF” wi = “ 59.10mm” /> 化学>(其中n和p分别为0至6的整数),其中X是包含1、2或3个烃衍生物链的结构,所述烃衍生物链的末端具有芳族氨基,并且在主链中可以具有碳-氮键Y为含有一个或多个硫原子的烃结构,Z为具有碳-碳键或碳-氧键的直链结构。具有还原端并通过芳族氨基与连接化合物结合的糖。
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