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Making use of the solid-state substrate which possesses the carboxyl group which is activated to the surface coat doing the micro array null solid-state base material which is produced the living body numerator with the manner which on the aforementioned solid-state substrate is fixed
Making use of the solid-state substrate which possesses the carboxyl group which is activated to the surface coat doing the micro array null solid-state base material which is produced the living body numerator with the manner which on the aforementioned solid-state substrate is fixed
Provided is a method for immobilizing a biomolecule on a solid substrate. The method includes coating the solid substrate with silane anhydride to introduce an anhydride functional group onto a surface of the solid substrate; obtaining a carboxyl group from the anhydride functional group by hydrolysis; reacting the carboxyl group with carbodiimide and succinimide to activate the carboxyl group; and contacting the biomolecule with the solid substrate having the activated carboxyl group on its surface to immobilize the biomolecule on the solid substrate. IMAGE
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