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In the oxazoline derivative of production mannered null
In the oxazoline derivative of production mannered null
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机译:在恶唑啉衍生物的生产中提倡无效
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摘要
PROBLEM TO BE SOLVED: To provide a method for easily mass-producing a β-1,6-bound N- acetyllactosamine oligosaccharide at a low cost.;SOLUTION: The β-1,6-bound N-acetyllactosamine oligosaccharide of the formula (1): Galβ-1-4(GlcNAcβ1-6Galβ1-4)nGlcNAc (wherein, Gal is a galactose residue; GlcAc is an N-acetylglucosamine residue; and (n) is 1-4) where N- acetyllactosamine is repeatedly bound via β-1,6 linkages is obtained by converting chitinase into an oxazoline derivative of N-acetyllactosamine under alkaline conditions to effect a transfer reaction into N-acetyllactosamine as the hydrolyzate of the oxazoline derivative. Further, β-D-galactosidase is reacted to the β-1,6-bound N-acetyllactosamine oligosaccharide to cleave the galactose residue on the non-reduced terminal, thus obtaining another type of β-1,6-bound N-acetyllactosamine oligosaccharide bearing N-acetylglucosamine on the non- reduced terminal.;COPYRIGHT: (C)2003,JPO
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