首页> 外国专利> chimaeres protein containing cysteine protease from large leberegel merged to the hepatitis b core protein or ubiquitin; plants that express this protein, and their use as vaccines

chimaeres protein containing cysteine protease from large leberegel merged to the hepatitis b core protein or ubiquitin; plants that express this protein, and their use as vaccines

机译：来自大型leberegel的含有半胱氨酸蛋白酶的chimaeres蛋白融合到了b型肝炎核心蛋白或泛素中;表达这种蛋白质的植物及其作为疫苗的用途

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摘要

The topic of the present invention is a chimaeric protein, sequence, construct, plant cell, a method for the production of the chimaeric protein and transgenic plant, the transgenic plant, and the application of transgenic plants to produce oral vaccines, pharmaceutical composition, vaccination against the liver fluke and a method for inducing immunity against liver fluke infections in mammals. In general, the present invention relates to a method for inducing an immune response, encompassing the application of vaccines through the gastrointestinal tract. The topics of the present invention serve to produce oral vaccines against the liver fluke.

机译：本发明的主题是嵌合蛋白，序列，构建体，植物细胞，生产嵌合蛋白和转基因植物的方法，转基因植物以及转基因植物在生产口服疫苗中的应用，药物组合物，疫苗接种对抗肝吸虫和诱导针对哺乳动物肝吸虫感染的免疫力的方法。总的来说，本发明涉及一种诱导免疫应答的方法，包括通过胃肠道应用疫苗。本发明的主题用于生产抗肝吸虫的口服疫苗。

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公开/公告号DE60314017D1

专利类型
公开/公告日2007-07-05

原文格式PDF
申请/专利权人 INSTITUTE OF BIOORGANIC CHEMISTRY;INSTITUTE OF BIOTECHNOLOGY ANTIBIOTICS;
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申请/专利号DE2003614017T
发明设计人 MIESZCZANEK JULIUSZ;POREBSKA ANNA;CZAPLINSKA MAGDALENA;KEZIK MALGORZATA;LEGOCKI ANDRZEJ B.;WEDRYCHOWICZ HALINA;MIEDZINSKA KATARZYNA;PLUCIENNICZAK ANDRZEJ;PNIEWSKITOMASZ;WOJCIECHOWICZ JACEK;MODELSKA ANNA;JEDLINA-PANASIUK LUIZA;
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申请日2003-12-04
分类号C12N15/82;A61K39/00;C07K14/02;C12N9/64;
国家 DE
入库时间 2022-08-21 20:27:35

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