首页> 外国专利> Method for iodinating substituted azole compound and acid addition compound by converting substituted 1H-triazoles compound, with an oxidizing agent and elementary iodine and/or iodine compound in presence of a solvent or its mixture

Method for iodinating substituted azole compound and acid addition compound by converting substituted 1H-triazoles compound, with an oxidizing agent and elementary iodine and/or iodine compound in presence of a solvent or its mixture

机译：在溶剂或其混合物存在下，通过将取代的1H-三唑化合物与氧化剂和单质碘和/或碘化合物转化为碘的取代的唑化合物和酸加成化合物的方法

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摘要

Method for iodinating substituted azole compound (I) or its salts and acid addition compounds by converting substituted 1H-triazoles (II) or its salts and acid addition compounds with oxidizing agent and elementary iodine and/or at least one iodine compound in presence of a solvent or its mixture at 0-200[deg]C. Method for iodinating substituted azole compound of formula (I) or its salts and acid addition compounds by converting substituted 1H-triazoles compound of formula (II) or its salts and acid addition compounds with at least one oxidizing agent and elementary iodine and/or at least one iodine compound in presence of a solvent or its mixture at 0-200[deg]C. A : N, CH or CR 3; B 1N, CH, CR 4or Cl; R 1alkenyl, alkynyl, (cyclo)alkyl, phenyl (all optionally substituted) or H; R 2I; and R 3, R 4alkenyl, alkynyl, (cyclo)alkyl, phenyl or phenyl ethyl (all optionally substituted). . Provided that at least one of A and B 1is N. [Image] ACTIVITY : Antibacterial. MECHANISM OF ACTION : None given.

机译：通过在氧化剂的存在下用氧化剂和单质碘和/或至少一种碘化合物转化取代的1H-三唑（II）或其盐和酸加成化合物来碘化取代的唑化合物（I）或其盐和酸加成化合物的方法溶剂或其混合物在0-200℃。通过将式（II）的取代的1H-三唑化合物或其盐和酸加成化合物与至少一种氧化剂和单质碘和/或在至少一个条件下转化来取代式（I）的取代的唑化合物或其盐和加成酸的方法在溶剂或其混合物存在下于0-200℃下的至少一种碘化合物。 A：N，CH或CR 3; B 1> N，CH，CR 4或Cl; R 1>烯基，炔基，（环）烷基，苯基（所有任选取代的）或H; R 2> I; R 3>，R 4>烯基，炔基，（环）烷基，苯基或苯乙基（均可选地被取代）。。前提是A和B 1>中的至少一个是N。[图像]活动：抗菌。作用机理：未给出。

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公开/公告号DE102006003444A1

专利类型
公开/公告日2007-07-26

原文格式PDF
申请/专利权人 LANXESS DEUTSCHLAND GMBH;
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申请/专利号DE20061003444
发明设计人 VOGL ERASMUS;
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申请日2006-01-25
分类号C07D257/04;C07D249/10;
国家 DE
入库时间 2022-08-21 20:29:28

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