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Detection method for specific biomolecular interactions using FRET between metal nanoparticle and quantum dot
Detection method for specific biomolecular interactions using FRET between metal nanoparticle and quantum dot
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机译:利用FRET检测金属纳米粒子与量子点之间特定生物分子相互作用的方法
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摘要
The present invention, a method for utilizing a pair of characteristics of the biomolecule to a pair of the energy receptor and the energy donor, specific binding indicating the FRET phenomenon, ① unknown determine whether specific binding between biomolecules ② a target molecule sample a method for detecting the presence of, and ③ a method for quantification of a target molecule present in the sample. ; According to the invention, which screen the biochemical substance in a quick and easy way without the labeling of the sample inhibit the specific binding between the pair of biomolecules with high speed and can be quantitatively analyzed and applied in new drug development, production in a number of cell can be applied or the like changes and quality inspection of the protein equivalent protein which is produced with the characteristic changes in accordance with analysis of the protein of the sugar used as a new drug candidate ; The metal nano-particles, quantum dots, fluorescent energy gongmyeongjeon this, glycoprotein, and high-speed screening
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