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Human Cell Binding Inhibitory Activity of Acne Bacillus and Atopic Staphylococcus aureus Containing Acidic Polysaccharides Isolated from Green Tea Leaves
Human Cell Binding Inhibitory Activity of Acne Bacillus and Atopic Staphylococcus aureus Containing Acidic Polysaccharides Isolated from Green Tea Leaves
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机译：痤疮芽孢杆菌和特应性金黄色葡萄球菌含有酸性多糖的人细胞结合抑制活性从绿茶叶中分离。
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摘要
A composition comprising an acidic polysaccharide is provided to show strong inhibition effect on hemagglutination caused by Propionibacterium acnes and Staphylococcus aureus without showing any inhibition effect on useful bacteria to human, thereby being usefully used for preventing and treating acne and atopic skin diseases. The composition for preventing and treating acne and atopic skin diseases comprises an acidic polysaccharide obtained by hot-water extracting crushed Camellia sinensis leaves and then precipitating the extract in ethanol. In the composition, the acidic polysaccharide is a fraction which is obtained by dissolving the ethanol precipitate in a phosphate buffer solution, dialyzing it and performing ion-exchange chromatography and gel-permeation chromatography thereon and has the activity of inhibiting human cellular interaction of Propionibacterium acnes and Staphylococcus aureus.
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