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- Animal Models Carrying Tumors Expressing Human Prostate Cancer-Specific Antigen and Method for Analyzing Prevention and Treatment Efficacy of Dendritic Cells-Derived Immunotherapeutics Using the Above
- Animal Models Carrying Tumors Expressing Human Prostate Cancer-Specific Antigen and Method for Analyzing Prevention and Treatment Efficacy of Dendritic Cells-Derived Immunotherapeutics Using the Above
Provided is a method for analyzing prevention and treatment efficacy of dendritic cells-derived immunotherapeutics using animal models carrying tumors expressing human prostate cancer-specific antigen(i.e., Mus musculus), to more accurately analyze the efficacy. The method for analyzing prevention and treatment efficacy of dendritic cells-derived immunotherapeutics comprises the steps of: administering a cancer cell line(tumor) expressing human prostate cancer-specific antigen to Mus musculus to cause the cancer; administering dendritic cells to a target with the cancer; and measuring cancer-cell formation and cancer cell growth(or proliferation) in the Mus musculus. Here, the human prostate cancer-specific antigen is one of PCA, PSCA, PSA, PAP, and PSMA.
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