首页> 外国专利> SELF-ASSEMBLED MONOLAYERS ON THE SURFACE OF GOLD COATED MICROCANTILEVERS FOR APPLICATION TO CHEMICAL SENSING AND METHOD OF PREPARATION

SELF-ASSEMBLED MONOLAYERS ON THE SURFACE OF GOLD COATED MICROCANTILEVERS FOR APPLICATION TO CHEMICAL SENSING AND METHOD OF PREPARATION

机译:用于化学传感的金包被微悬臂梁表面上的自组装单分子膜及其制备方法

摘要

Methods for the preparation of a stable, self-assembled monolayer on the silicon surface or metallic coating of a microcantilever are disclosed. The methods produce a microcantilever suitable as a chemical sensor. In a microcantilever produced using one version of the method, a metallic coating is disposed on a side of the microcantilever, a bridging atom is bonded to the metallic coating, a first spacer group is bonded to the bridging atom, a second spacer group is bonded to the bridging atom, and a chemical recognition agent is bonded to the first spacer group. In another version of the method, a silicon surface of a microcantilever is hydrogen terminated, and a calixarene chemical recognition agent is carbon linked to the silicon surface using photochemical hydrosilylation. Among other things, the calixarene may be bonded to a crown ether for ion detection or bonded to a urea for the recognition of explosives by hydrogen bonding to nitro groups.
机译:公开了在微悬臂梁的硅表面或金属涂层上制备稳定的,自组装单层的方法。该方法产生适合用作化学传感器的微悬臂梁。在使用一种方法的方法制备的微悬臂梁中,在微悬臂梁的侧面上设置金属涂层,将桥接原子键合至金属涂层,将第一间隔基团键合至桥接原子,将第二间隔基团键合原子连接至桥连原子,并且化学识别剂键合至第一间隔基团。在该方法的另一种形式中,微悬臂梁的硅表面是氢封端的,而杯芳烃化学识别剂是通过光化学氢化硅烷化作用与硅表面连接的碳。其中,杯芳烃可以结合至冠醚以进行离子检测,或结合至脲以通过氢键合至硝基而识别爆炸物。

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