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TUMOR MARKER, DIAGNOSTIC KIT FOR TUMOR, METHOD FOR DETERMINATION OF TUMOR MARKER, AND DIAGNOSTIC METHOD FOR TUMOR

机译:肿瘤标记物,用于肿瘤的诊断工具,确定肿瘤标记物的方法以及用于肿瘤的诊断方法

摘要

Disclosed is a tumor marker having high sensitivity and high specificity. The tumor marker comprises at least one substance selected from a human sideroflexin, an anti-human sideroflexin antibody, a human sideroflexin gene and mRNA for the gene. The human sideroflexin is preferably sideroflexin-3. The antibody is preferably an autoantibody contained in the serum. For example, an autoantibody contained in the serum of a subject may be determined by ELISA using recombinant sideroflexin-3 as an antigen, whereby cancer can be detected with high sensitivity and high specificity as shown in the graph of Fig. 1.
机译:公开了具有高灵敏度和高特异性的肿瘤标志物。所述肿瘤标志物包含至少一种选自人铁单宁素,抗人铁单宁素抗体,人铁单宁素基因和该基因的mRNA的物质。人铁弹性体屈曲素优选是铁弹性体屈曲素-3。抗体优选是血清中包含的自身抗体。例如,受试者的血清中所含的自身抗体可以通过使用重组sideroflexin-3作为抗原的ELISA来确定,从而可以如图1的图所示以高灵敏度和高特异性来检测癌症。

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