首页> 外国专利> PREVENTIVE OR THERAPEUTIC AGENT FOR SIDE EFFECT BASED ON CYTOTOXICITY OF ANTICANCER THERAPY CONTAINING APOPTOSIS INHIBITION ACTIVITY-ENHANCING PROTEIN FNK OR NUCLEIC ACID ENCODING THE SAME

PREVENTIVE OR THERAPEUTIC AGENT FOR SIDE EFFECT BASED ON CYTOTOXICITY OF ANTICANCER THERAPY CONTAINING APOPTOSIS INHIBITION ACTIVITY-ENHANCING PROTEIN FNK OR NUCLEIC ACID ENCODING THE SAME

机译:基于抗凋亡治疗的细胞毒作用,包含凋亡抑制活性,可增强蛋白质FNK或编码其的核酸,具有预防或治疗副作用的作用

摘要

It is intended to provide a preventive or therapeutic agent for a side effect based on the cytotoxicity of anticancer therapy containing apoptosis inhibition activity-enhancing protein FNK or a nucleic acid encoding the same. The preventive or therapeutic agent for a side effect based on the cytotoxicity of anticancer therapy containing, as an active ingredient, FNK protein, in which at least one replacement selected from the replacement of Tyr-22 with Phe, the replacement of Gln-26 with Asn and the replacement of Arg-165 with Lys in Bcl-xL protein is contained, or a nucleic acid encoding the same.
机译:旨在提供基于抗癌疗法的细胞毒性的副作用的预防或治疗剂,所述抗癌疗法包含凋亡抑制活性增强蛋白FNK或编码该蛋白的核酸。以抗癌疗法的细胞毒性为基础的副作用的预防或治疗药,其含有FNK蛋白作为有效成分,其中至少一种替代物选自用Phe替代Tyr-22,用Phe替代Gln-26。包含Asn或Bcl-xL蛋白中的Lys置换Arg-165,或包含编码Asn的核酸。

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