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HOMOEOLOGOUS REGION JUDGING METHOD BY HOMO JUNCTION FINGERPRINT METHOD, HOMOEOLOGOUS REGION JUDGING DEVICE, AND GENE SCREENING METHOD
HOMOEOLOGOUS REGION JUDGING METHOD BY HOMO JUNCTION FINGERPRINT METHOD, HOMOEOLOGOUS REGION JUDGING DEVICE, AND GENE SCREENING METHOD
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机译:均势指印法,均势区判断装置和基因筛选方法的均势区判断方法
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摘要
[PROBLEMS] To provide a method for efficiently searching for a recessive disease gene without needing any pedigree analysis. [MEANS FOR SOLVING PROBLEMS] In a homoeologous region judging method, the following steps are conducted. It is judged whether or not the base constituting a polymorphic marker of a sample DNA of diploid or higher polyploidy is a homojunction. Homojunction region information representing the region of the sample DNA where polymorphic markers judged as homojunctions continue is acquired. If the continuous probability and/or continuous distance of the polymorphic markers contained in the homojunction region information satisfy a predetermined judgment condition, the homojunction region is judged as a homoeologous region. A homoeologous region judging device and a gene screening method for identifying a disease susceptibility gene from the judged homoeologous region are also provided.
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