首页> 外国专利> NOVEL TARGETS AND COMPOUNDS USEFUL IN THE TREATMENT AND/OR PROPHYLAXIS OF A CARDIOVASCULAR DISORDER, DYSLIPIDEMIA AND ATHEROSCLEROSIS, AND METHODS TO IDENTIFY SUCH COMPOUNDS

NOVEL TARGETS AND COMPOUNDS USEFUL IN THE TREATMENT AND/OR PROPHYLAXIS OF A CARDIOVASCULAR DISORDER, DYSLIPIDEMIA AND ATHEROSCLEROSIS, AND METHODS TO IDENTIFY SUCH COMPOUNDS

机译：在心血管疾病，血脂异常和动脉粥样硬化的治疗和/或预防中有用的新靶标和化合物，以及鉴定此类化合物的方法

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摘要

The present invention provides targets and methods for the screening for compounds useful in the prevention, amelioration or treatment and/or prophylaxis of a cardiovascular disorder, dyslipidemia, and/or Atherosclerosis. The invention also relates to the targets that were identified. Inhibiting or activating target genes of the invention, or their expression products, by using compounds identifiable by methods of the invention, is beneficial in the treatment and/or prophylaxis of diseases involving a cardiovascular disorder, dyslipidemia, and/or Atherosclerosis.

机译：本发明提供了用于筛选可用于预防，改善或治疗和/或预防心血管疾病，血脂异常和/或动脉粥样硬化的化合物的靶标和方法。本发明还涉及所识别的目标。通过使用可通过本发明的方法鉴定的化合物来抑制或激活本发明的靶基因或其表达产物，对于治疗和/或预防涉及心血管疾病，血脂异常和/或动脉粥样硬化的疾病是有益的。

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公开/公告号WO2007000292A2

专利类型
公开/公告日2007-01-04

原文格式PDF
申请/专利权人 GALAPAGOS NV;BETZ ULRICH;DURSO DONATELLA;GATSIOS PETROS;SEEWALD MICHAEL;STRAYLE JOCHEN;VAN ES HELMUTH HENDRIKUS GERARDUS;VAN ZUTPHEN MARLIJN;MESIC EMIR;
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申请/专利号WO2006EP06117
发明设计人 BETZ ULRICH;DURSO DONATELLA;GATSIOS PETROS;SEEWALD MICHAEL;STRAYLE JOCHEN;VAN ES HELMUTH HENDRIKUS GERARDUS;VAN ZUTPHEN MARLIJN;MESIC EMIR;
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申请日2006-06-24
分类号C12Q1/48;A61K48;A61P3;A61P9;
国家 WO
入库时间 2022-08-21 20:51:45

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