首页> 外国专利> Cancerous disease modifying antibodies for diagnostic and therapeutic use in breast and ovarian cancer

Cancerous disease modifying antibodies for diagnostic and therapeutic use in breast and ovarian cancer

机译:用于乳腺癌和卵巢癌的诊断和治疗用途的癌变抗体

摘要

The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell cytotoxicity as an end point, the process makes possible the production of anti-cancer antibodies for therapeutic and diagnostic purposes. The antibodies can be used in aid of staging and diagnosis of a cancer, and can be used to treat primary tumors and tumor metastases. The anti-cancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, and hematogenous cells.
机译:本发明涉及一种使用新型筛选范例产生患者癌症疾病修饰抗体的方法。通过使用癌细胞的细胞毒性作为终点分离抗癌抗体,该方法使得产生用于治疗和诊断目的的抗癌抗体成为可能。抗体可用于辅助癌症的分期和诊断,并可用于治疗原发性肿瘤和肿瘤转移。可以将抗癌抗体与毒素,酶,放射性化合物和血细胞结合。

著录项

  • 公开/公告号AU2007222843A1

    专利类型

  • 公开/公告日2007-09-13

    原文格式PDF

  • 申请/专利权人 F. HOFFMANN-LA ROCHE AG;

    申请/专利号AU20070222843

  • 申请日2007-03-05

  • 分类号C07K16/30;A61K39/395;A61K47/48;A61K51/10;A61P35;

  • 国家 AU

  • 入库时间 2022-08-21 20:52:44

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