首页> 外国专利> PNEUMOCOCCAL POLYSACCHARIDE-RECOMBINANT PNEUMOLYSIN CONJUGATE VACCINES FOR IMMUNIZATION AGAINST PNEUMOCOCCAL INFECTIONS

PNEUMOCOCCAL POLYSACCHARIDE-RECOMBINANT PNEUMOLYSIN CONJUGATE VACCINES FOR IMMUNIZATION AGAINST PNEUMOCOCCAL INFECTIONS

机译：肺炎球菌多糖重组肺炎球菌溶血素共轭疫苗，用于针对肺炎球菌感染的免疫接种。

页面导航

摘要
著录项
相似文献

摘要

Immunogenic polysaccharide-protein conjugates are generated which have anoxidized polysaccharide derived from the capsularpolysaccharide of Streptococcal pneumoniae and the pneumolysin protein of S.pneumoniae wbich is expressed recombinantly. Thepneumolysin is not toxoided prior to conjugation with said oxidizedpolysaccharide. The immunogenic conjugates are used as vaccinesto elicit antibody responses to the capsular polysaccharide of S. pneumoniaeand to recombinant pneumolysin, and to immunize against S.pneumoniae-caused disease.

机译：产生的免疫原性多糖-蛋白质结合物具有荚膜衍生的氧化多糖肺炎链球菌多糖和肺炎链球菌溶血素蛋白。肺炎克雷伯菌是重组表达的。的肺炎球菌溶血素在与所说的氧化物结合之前不被类毒素多糖。免疫原性缀合物用作疫苗引起针对肺炎链球菌荚膜多糖的抗体反应并重组肺炎球菌溶血素，并针对S进行免疫。肺炎引起的疾病。

著录项

公开/公告号CA2198251C

专利类型
公开/公告日2007-06-12

原文格式PDF
申请/专利权人 AMERICAN CYANAMID COMPANY;
展开▼

申请/专利号CA19952198251
发明设计人 KUO JOSEPH S.-C.;REE HEESOO K.;
展开▼

申请日1995-08-10
分类号C07K14/315;A61K39/09;C07K16/12;C08B37/00;C12P19/04;A61K39/00;
国家 CA
入库时间 2022-08-21 20:54:19

相似文献

专利
外文文献
中文文献