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Pharmacology works including buprenorphine

机译:药理学著作,包括丁丙诺啡

摘要

It refers to a kind of drug synthesis, including: (a) buprenorphine, which is 0.1-10% of the formula; (b) a solvent, which is composed of water phase and organic phase, such as 2-pyrrolidine, diethylmethylamine, N-methylpyrrolidine, propylene glycol, etc, By formula weight, the content is between 10% and 75%; (c) an enhanced penetrant including fat and / or hydrolytic components, such as propylene glycol monolaurate, mantol, ethanol, lauryl alcohol, etc.; and (d) a stabilizer, such as Butyl carbamate (BHA),1. Hydroxytoluene butadiene (BHT) and sodium monothiocarbinol; (E) a preservative, such as methyl-p-benzene, propyl-p-benzene, etc.; (f) a viscosity enhancer, such as hydroxypropyl cellulose; (g) a non opioid analysis, such as acetylhydrazine, cilomycete, pyridoxine, etc; The pH value of this pharmacological component is 3-10, which is useful through the analysis of otica and transdermica management system.
机译:它是指一种药物合成方法,包括:(a)丁丙诺啡,占配方的0.1-10%; (b)由水相和有机相组成的溶剂,例如2-吡咯烷,二乙基甲胺,N-甲基吡咯烷,丙二醇等,按配方重量计,含量在10%至75%之间; (c)增强的渗透剂,包括脂肪和/或水解成分,例如单月桂酸丙二醇酯,曼托尔,乙醇,月桂醇等; (d)稳定剂,例如氨基甲酸丁酯(BHA),1。羟基甲苯丁二烯(BHT)和单硫代甲醇钠; (E)防腐剂,例如甲基对苯,丙基对苯等; (f)粘度增强剂,例如羟丙基纤维素; (g)非阿片类药物的分析,例如乙酰肼,纤毛虫,吡ido醇等;该药理成分的pH值为3-10,可通过分析耳色和透皮管理系统来使用。

著录项

  • 公开/公告号PE20070643A1

    专利类型

  • 公开/公告日2007-08-10

    原文格式PDF

  • 申请/专利权人 SCHERING-PLOUGH LTD.;

    申请/专利号PE2006001462

  • 申请日2006-11-16

  • 分类号A61K9;A61K31/485;A61P29;

  • 国家 PE

  • 入库时间 2022-08-21 20:56:41

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