首页> 外国专利> anion-binding polymer, pharmaceutical composition, ion-phosphate-binding polymers, and methods for measuring interference to the target ion-binding polymer for an ion-binding polymer by selecting an ion-binding polymer that binds to a target ion for improving the therapeutic properties and / or suitability for administration and / or pharmaceutical properties of a polyamenic polymer, of making an ion-binding polymer that binds to a target anion, and of removing an anion from an animal

anion-binding polymer, pharmaceutical composition, ion-phosphate-binding polymers, and methods for measuring interference to the target ion-binding polymer for an ion-binding polymer by selecting an ion-binding polymer that binds to a target ion for improving the therapeutic properties and / or suitability for administration and / or pharmaceutical properties of a polyamenic polymer, of making an ion-binding polymer that binds to a target anion, and of removing an anion from an animal

机译：阴离子结合聚合物，药物组合物，离子磷酸盐结合聚合物以及通过选择与目标离子结合的离子结合聚合物来改善对治疗剂的离子结合聚合物对目标离子结合聚合物的干扰的测量方法聚酰胺聚合物的化学性质和/或给药和/或药学性质的适应性，制备与目标阴离子结合的离子结合聚合物以及从动物中去除阴离子

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"ANION-BINDING POLYMER, PHARMACEUTICAL COMPOSITION, Phosphate and ION-BINDING POLYMERS, AND METHODS FOR MEASURING ION-BINDING INTERFERENCE FOR AN ION-ION-BIN-POLYMON-BINDING SELECTION POLYMER TARGET, FOR IMPROVEMENT OF THERAPEUTIC PROPERTIES AND / OR FITNESS FOR ADMINISTRATION AND / OR PHARMACEUTICAL PROPERTIES OF MANUFACTURING A POLYAMIC POLYMER, CONNECTING TO A ION, A NON-AIM, AND A REAL AIM, Description of anion binder (chelating) polymers. In some cases, anion-binding polymers are low swelling polymers. In some cases, such anion-binding polymers have a pore volume distribution such that a fraction of the polymer is not available for non-interacting solutes greater than a given percentage molecular weight of the polymer target ion. Anion-binding polymers are characterized by low interference with anion binding when such interference is measured, for example, by means of a pseudo-gastrointestinal agent, when compared to that measured in a non-interfering buffer. The patent also describes the pharmaceutical composition, the methodology of use and kits.

机译：“结合阴离子的聚合物，药物组合物，磷酸盐和结合离子的聚合物，以及测量结合离子对离子-聚合物结合选择聚合物目标的结合干扰的方法，以改善治疗性质和/或适用性制造多聚体聚合物，连接到离子，非目标和真实目标的和/或药物特性，描述阴离子粘合剂（螯合）聚合物，在某些情况下，阴离子结合聚合物是低溶胀聚合物。在这种情况下，这种阴离子键合聚合物的孔体积分布使得对于大于分子量目标离子给定分子量百分比的非相互作用溶质而言，该聚合物的一部分不可得。当与例如在非干扰缓冲液中测量的相比时，例如通过伪胃肠道试剂测量这种干扰时的阴离子结合。包括药物成分，使用方法和试剂盒。

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公开/公告号BRPI0416172A

专利类型
公开/公告日2007-01-16

原文格式PDF
申请/专利权人 ILYPSA INC.;
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申请/专利号BR2004PI16172
发明设计人 ERIC CONNOR;DOMINIQUE CHARMOT;HAN TING CHANG;FLORENCE ROGER;GERRIT KLEARNER;SON HOAL NGUYEN;
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申请日2004-11-03
分类号C08G73/00;
国家 BR
入库时间 2022-08-21 20:59:28

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