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Compositions and methods for enhanced dendritic cell maturation and function

机译:用于增强树突状细胞成熟和功能的组合物和方法

摘要

This invention relates to compositions comprising an agent, which inhibits signaling via the FcγRIIB receptor and an agent which stimulates or enhances signaling via an FcγRI receptor, an FcγRIIa receptor, an FcγRIII receptor, or a combination thereof. The invention also provides for the use of such compositions in stimulating or enhancing an immune response, and in treating, suppressing, or preventing cancer in a subject.
机译:本发明涉及包含通过FcγRIIB受体抑制信号传导的药物和通过FcγRI受体,FcγRIIa受体,FcγRIII受体或其组合刺激或增强信号传导的药物的组合物。本发明还提供了此类组合物在刺激或增强免疫应答以及治疗,抑制或预防受试者的癌症中的用途。

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