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Regulation of guanine nucleotide exchange factor for a protein belonging to the rap family of small gtpases

机译：鸟嘌呤核苷酸交换因子对小gtpases rap家族蛋白的调控

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摘要

The invention relates generally to the methods of treating brain diseases and compounds for treating brain diseases, and more specifically relates to using compounds that are able to modulate guanine nucleotide exchange factors for proteins belonging to the Rap family of small GTPases to treat diseases of the brain, such as Alzheimer's and Schizophrenia.

机译：本发明总体上涉及治疗脑疾病的方法和用于治疗脑疾病的化合物，并且更具体地涉及使用能够调节属于小GTPase的Rap家族的蛋白质的鸟嘌呤核苷酸交换因子的化合物来治疗脑疾病，例如老年痴呆症和精神分裂症。

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公开/公告号US2007197482A1

专利类型
公开/公告日2007-08-23

原文格式PDF
申请/专利权人 IAN MCPHEE;CATHERINE BRESLIN;JUSTIN PETER KEWNEY;SIMON JOHN MACKENZIE;ANN COOREMAN;LUCIEN CHARLES DONALD GIBSON;MORAG MCFARLANE;STEPHEN HAMMOND;
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申请/专利号US20040555371
发明设计人 IAN MCPHEE;CATHERINE BRESLIN;JUSTIN PETER KEWNEY;SIMON JOHN MACKENZIE;ANN COOREMAN;LUCIEN CHARLES DONALD GIBSON;MORAG MCFARLANE;STEPHEN HAMMOND;
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申请日2004-05-04
分类号A61K31/655;A61K31/5377;A61K31/519;A61K31/428;A61K31/425;A61K31/426;A61K31/12;C07D487/02;C07D417/02;
国家 US
入库时间 2022-08-21 21:05:41

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