首页> 外国专利> Inversion on chromosome 8p23 is a risk factor for anxiety disorders, depression and bipolar disorders

Inversion on chromosome 8p23 is a risk factor for anxiety disorders, depression and bipolar disorders

机译:8p23染色体倒位是焦虑症,抑郁症和双相情感障碍的危险因素

摘要

An association between psychiatric disorders and disorders comorbid with psychiatric disorders, and genetic markers in the 8p23 genomic region is described. Markers are also provided to diagnose or detect a susceptibility to disorders comorbid with panic disorder and independently of comorbidity with panic disorder. Methods and surrogate markers for detecting the orientation of the Inv8p23 inversion fragment, thereby diagnosing psychiatric disorders or comorbid disorders or a susceptibility to psychiatric disorders or comorbid disorders, are also disclosed. The methods described herein are also useful for determining responsiveness of drugs useful for treating psychiatric disorders.
机译:描述了精神疾病和与精神疾病合并的疾病之间的关联,并描述了8p23基因组区域的遗传标记。还提供了标记物,以诊断或检测与恐慌症合并症且与惊恐症合并症无关的易感性。还公开了用于检测Inv8p23倒位片段的方向从而诊断精神疾病或合并症或对精神疾病或合并症的易感性的方法和替代标记。本文所述的方法还可用于确定可用于治疗精神疾病的药物的反应性。

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