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Method of accumulating allergen-specific t cell antigen determinant in plant and plant having the antigen determinant accumulated therein
Method of accumulating allergen-specific t cell antigen determinant in plant and plant having the antigen determinant accumulated therein
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机译：在植物中积累过敏原特异性t细胞抗原决定簇的方法以及其中积累了抗原决定簇的植物
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摘要
Disclosed herein are techniques for accumulating a human T-cell epitope in rice albumen, particularly a method of directly accumulating a T-cell epitope-linked peptide, such as 7 Crp, in rice seeds and a method of inserting 7 Crp into a variable region of glutelin, the major storage protein of rice, to express and accumulate 7 Crp as a part of the glutelin storage protein. Rice producing the T-cell epitope-linked peptide developed in accordance with the present invention is expected to function as an edible vaccine against Japanese cedar pollinosis.
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