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POLYMER CROSS-LINKING AGENT AND LIPOSOME OR CELL CROSS-LINKED PRODUCT USING THE CROSS-LINKING AGENT

机译:聚合物交联剂和使用该交联剂的脂质体或细胞交联产品

摘要

PROBLEM TO BE SOLVED: To solve a problem that biological polymer cross-linked products prepared by chemically cross-linking biological polymers such as collagen or gelatin through covalent bonds strongly denaturate proteins or damage cells because of being prepared with the covalent bonds, while the biological polymer cross-linked products have been used as a material for the sustained release of proteins or as a three-dimensional culture carrier to perform the sustained release of protein preparations or the regeneration of biological tissues.;SOLUTION: The polymer cross-linking agent having a hydrophobic portion and a hydrophilic portion in one molecule is synthesized and then used to physically cross-link cells, liposomes or cell-liposome mixtures which are lipid aggregates.;COPYRIGHT: (C)2007,JPO&INPIT
机译:要解决的问题:解决以下问题:通过共价键化学交联胶原蛋白或明胶之类的生物聚合物而制备的生物聚合物交联产物,由于具有共价键而被制备,从而强烈地变性蛋白质或损害细胞,而生物聚合物交联产品已用作蛋白质持续释放的材料或用作三维培养载体以进行蛋白质制剂的持续释放或生物组织的再生。合成一个分子中的疏水部分和亲水部分,然后将其物理交联为脂质聚集体的细胞,脂质体或细胞-脂质体混合物。版权所有:(C)2007,JPO&INPIT

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