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1-Aminocyclohexane derivatives for the treatment of agitation and other behavioral disorders, especially behavioral disorders associated with Alzheimer's disease

机译:1-氨基环己烷衍生物,用于治疗躁动和其他行为障碍,尤其是与阿尔茨海默氏病相关的行为障碍

摘要

The present invention relates to the treatment of behavioral disorders, especially agitation, associated with a central nervous system (CNS) disorder, especially Alzheimer's disease (AD), cerebrovascular disease (VaD), or Down's Syndrome, in a mammal, comprising administering to said mammal an 1-aminocyclohexane, alone or in combination with a acetylcholinesterase inhibitor. In one embodiment, the 1-aminocyclohexane is memantine.
机译:本发明涉及在哺乳动物中与中枢神经系统(CNS)疾病,特别是阿尔茨海默氏病(AD),脑血管疾病(VaD)或唐氏综合症有关的行为障碍,特别是躁动的治疗,包括给予所述哺乳动物单独或与乙酰胆碱酯酶抑制剂组合的1-氨基环己烷。在一个实施方案中,1-氨基环己烷是美金刚。

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